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        <title>Annals of Surgical Innovation and Research - Most accessed articles</title>
        <link>http://www.asir-journal.com</link>
        <description>The most accessed research articles published by Annals of Surgical Innovation and Research</description>
        <dc:date>2012-01-04T00:00:00Z</dc:date>
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        <title>Management of complications after laparoscopic Nissen&apos;s fundoplication: a surgeon&apos;s perspective</title>
        <description>IntroductionGastro-oesophageal reflux disease (GORD) is a common problem in the Western countries, and the interest in the minimal access surgical approaches to treat GORD is increasing. In this study, we would like to discuss the presentations and management of complications we encountered after Laparoscopic Nissen&apos;s fundoplication in our District General NHS Hospital. The aim is to recognise these complications at the earliest stage for effective management to minimise the morbidity and mortality.
Methods:
301 patients underwent laparoscopic treatment for GORD by a single consultant surgeon in our NHS Trust from September 1999. The data was prospectively collected and entered into a database. The data was retrospectively analysed for presentations for complications and their management.
Results:
Surgery was completed laparoscopically in all patients, except in five, where the operation was technically difficult due to pre-existing conditions. The complications we encountered during surgery and follow-up period were major intra-operative bleeding (n = 1, 0.33%), severe post-operative nausea and vomiting (n = 1, 0.33%), wound infection (n = 3, 1%), port-site herniation (n = 1, 0.33%), wrap-migration (n = 2, 0.66%), wrap-ischaemia (n = 1, 0.33%), recurrent regurgitation (n = 4, 1.32%), recurrent heartburn (n = 29, 9.63%), tension pneumothorax (n = 2, 0.66%), surgical emphysema (n = 8, 2.66%), and port-site pain (n = 4, 1.33%).
Conclusion:
Minimal access approach to treat GORD has presented with some specific and unique complications. It is important to recognise these complications at the earliest possible stage as some of these patients may present in an acute setting requiring emergency surgery. All members of the department, and not just the members of the specialised team, should be aware about these complications to minimise the morbidity and mortality.</description>
        <link>http://www.asir-journal.com/content/3/1/1</link>
                <dc:creator>Tarun Singhal</dc:creator>
                <dc:creator>Santosh Balakrishnan</dc:creator>
                <dc:creator>Abdulzahra Hussain</dc:creator>
                <dc:creator>Starlene Grandy-Smith</dc:creator>
                <dc:creator>Andrew Paix</dc:creator>
                <dc:creator>Shamsi El-Hasani</dc:creator>
                <dc:source>Annals of Surgical Innovation and Research 2009, null:1</dc:source>
        <dc:date>2009-02-04T00:00:00Z</dc:date>
        <dc:identifier>doi:10.1186/1750-1164-3-1</dc:identifier>
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        <item rdf:about="http://www.asir-journal.com/content/6/1/1">
        <title>Emergency incisional hernia repair: A difficult problem waiting for a solution</title>
        <description>Background:
Emergency repair of incarcerated incisional hernia with associated bowel obstruction in potentially or contaminated field is technically challenging due to edematous, inflamed and friable tissues with occasional need for concurrent bowel resection and carries high rates of post-operative infectious complications. The aim of this study was to retrospectively assess the wound related morbidity of use of permanent prosthetic mesh in emergency repair of incarcerated incisional hernia with associated bowel obstruction. We also describe a new technique of leaving the mesh exposed to heal by secondary intention with granulation tissue.
Methods:
Between 2000 and 2010 a total of 60 patients underwent emergency surgery for incarcerated incisional hernia with associated bowel obstruction with placement of permanent prosthetic mesh. The wound was closed after hernia repair in 55 patients while it was left open to granulate in 5 patients.
Results:
In the group of patients with primary wound closure, 11 patients developed superficial surgical site infection, 5 developed deep wound infection and one patient had cellulitis. These patients were treated with wound debridement and antibiotics. Mesh removal was required in one patient. There were no infections in the group of patients who had their surgical wounds left open. One patient in this group died on the fifth postoperative day from septicemia.
Conclusion:
Use of permanent prosthetic mesh in emergency repair of incarcerated incisional hernia with associated bowel obstruction. in contaminated field is associated with high risk of wound infection.</description>
        <link>http://www.asir-journal.com/content/6/1/1</link>
                <dc:creator>Hasnain Zafar</dc:creator>
                <dc:creator>Masooma Zaidi</dc:creator>
                <dc:creator>Irfan Qadir</dc:creator>
                <dc:creator>Ayaz Memon</dc:creator>
                <dc:source>Annals of Surgical Innovation and Research 2012, null:1</dc:source>
        <dc:date>2012-01-04T00:00:00Z</dc:date>
        <dc:identifier>doi:10.1186/1750-1164-6-1</dc:identifier>
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        <title>A new surgical ventricular restoration technique to reset residual myocardium&apos;s fiber orientation: the &quot;KISS&quot; procedure</title>
        <description>Background:
The history of surgical reconstruction of the left ventricle after an anterior myocardial infarction shows an evolution of techniques which tend to a more and more physiologic restoration of ventricular shape and volume, with increasing attention to the orientation of myocardial fibers.
Methods:
We set a new surgical procedure for endoventricular patch reconstruction technique with the aim to rebuild a physiologic shape and volume of the left ventricle caring about realignment of myocardial fibers orientation. Peculiarities of this reconstruction are the shape of the patch (reduction of minor axis compared with currently used oval-shaped patch) and the asymmetrical way of suturing it inside the ventricle.
Results:
We present a detailed description of operative steps of this procedure, and we add some relevant surgical hints to clarify its peculiarities. Most of the patients operated on with this technique showed the original renewal of apical rotation and left ventricular torsion as specific index of the restoration of physiologic fiber orientation: we report an exemplary case of at-sight recovery of apical rotation in the operating room.
Conclusion:
This technique can represent a reproducible new way to realign myocardial fibers in a near-normal setting, improving the physiological restoration of ischemically injured left ventricle. It could be also the basis to reconsider surgical treatment for heart failure.</description>
        <link>http://www.asir-journal.com/content/3/1/6</link>
                <dc:creator>Marco Cirillo</dc:creator>
                <dc:source>Annals of Surgical Innovation and Research 2009, null:6</dc:source>
        <dc:date>2009-06-23T00:00:00Z</dc:date>
        <dc:identifier>doi:10.1186/1750-1164-3-6</dc:identifier>
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        <item rdf:about="http://www.asir-journal.com/content/3/1/12">
        <title>Fibrin glue in the treatment of anal fistula: a systematic review</title>
        <description>Background:
New sphincter-saving approaches have been applied in the treatment of perianal fistula in order to avoid the risk of fecal incontinence. Among them, the fibrin glue technique is popular because of its simplicity and repeatability. The aim of this review is to compare the fibrin glue application to surgery alone, considering the healing and complication rates.
Methods:
We performed a systematic review searching for published randomized and controlled clinical trials without any language restriction by using electronic databases. All these studies were assessed as to whether they compared conventional surgical treatment versus fibrin glue treatment in patients with anal fistulas, in order to establish both the efficacy and safety of each treatment. We used Review Manager 5 to conduct the review.
Results:
The healing rate is higher in those patients who underwent the conventional surgical treatment (P = 0,68), although the treatment with fibrin glue gives no evidence of anal incontinence (P = 0,08). Furthermore two subgroup analyses were performed: fibrin glue in combination with intra-adhesive antibiotics versus fibrin glue alone and anal fistula plug versus fibrin glue. In the first subgroup there were not differences in healing (P = 0,65). Whereas in the second subgroup analysis the healing rate is statistically significant for the patients who underwent the anal fistula plug treatment instead of the fibrin glue treatment (P = 0,02).
Conclusion:
In literature there are only two randomized controlled trials comparing the conventional surgical management versus the fibrin glue treatment in patients with anal fistulas. Although from our statistical analysis we cannot find any statistically significant result, the healing rate remains higher in patients who underwent the conventional surgical treatment (P = 0,68), and the anal incontinence rate is very low in the fibrin glue treatment group (P = 0,08). Anyway the limited collected data do not support the use of fibrin glue. Moreover, in our subgroup analysis the use of fibrin glue in combination with intra-adhesive antibiotics does not improve the healing rate (P = 0.65), whereas the anal fistula plug treatment compared to the fibrin glue treatment shows good results (P = 0,02), although the poor number of patients treated does not lead to any statistically evident conclusion. This systematic review underlines the need of new RCTs upon this issue.</description>
        <link>http://www.asir-journal.com/content/3/1/12</link>
                <dc:creator>Roberto Cirocchi</dc:creator>
                <dc:creator>Eriberto Farinella</dc:creator>
                <dc:creator>Francesco La Mura</dc:creator>
                <dc:creator>Lorenzo Cattorini</dc:creator>
                <dc:creator>Barbara Rossetti</dc:creator>
                <dc:creator>Diego Milani</dc:creator>
                <dc:creator>Patrizia Ricci</dc:creator>
                <dc:creator>Piero Covarelli</dc:creator>
                <dc:creator>Marco Coccetta</dc:creator>
                <dc:creator>Giuseppe Noya</dc:creator>
                <dc:creator>Francesco Sciannameo</dc:creator>
                <dc:source>Annals of Surgical Innovation and Research 2009, null:12</dc:source>
        <dc:date>2009-11-14T00:00:00Z</dc:date>
        <dc:identifier>doi:10.1186/1750-1164-3-12</dc:identifier>
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        <prism:startingPage>12</prism:startingPage>
        <prism:publicationDate>2009-11-14T00:00:00Z</prism:publicationDate>
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        <item rdf:about="http://www.asir-journal.com/content/4/1/2">
        <title>Vascular clamping in liver surgery: physiology, indications and techniques</title>
        <description>This article reviews the historical evolution of hepatic vascular clamping and their indications. The anatomic basis for partial and complete vascular clamping will be discussed, as will the rationales of continuous and intermittent vascular clamping.Specific techniques discussed and described include inflow clamping (Pringle maneuver, extra-hepatic selective clamping and intraglissonian clamping) and outflow clamping (total vascular exclusion, hepatic vascular exclusion with preservation of caval flow). The fundamental role of a low Central Venous Pressure during open and laparoscopic hepatectomy is described, as is the difference in their intra-operative measurements. The biological basis for ischemic preconditioning will be elucidated. Although the potential dangers of vascular clamping and the development of modern coagulation devices question the need for systemic clamping; the pre-operative factors and unforseen intra-operative events that mandate the use of hepatic vascular clamping will be highlighted.</description>
        <link>http://www.asir-journal.com/content/4/1/2</link>
                <dc:creator>Elie Chouillard</dc:creator>
                <dc:creator>Andrew Gumbs</dc:creator>
                <dc:creator>Daniel Cherqui</dc:creator>
                <dc:source>Annals of Surgical Innovation and Research 2010, null:2</dc:source>
        <dc:date>2010-03-26T00:00:00Z</dc:date>
        <dc:identifier>doi:10.1186/1750-1164-4-2</dc:identifier>
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        <prism:startingPage>2</prism:startingPage>
        <prism:publicationDate>2010-03-26T00:00:00Z</prism:publicationDate>
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        <item rdf:about="http://www.asir-journal.com/content/5/1/4">
        <title>Comparing ambient, air-convection, and fluid-convection heating techniques in treating hypothermic burn patients, a clinical RCT</title>
        <description>Background:
Hypothermia in burns is common and increases morbidity and mortality. Several methods are available to reach and maintain normal core body temperature, but have not yet been evaluated in critical care for burned patients. Our unit&apos;s ordinary technique for controlling body temperature (Bair Hugger&#174;+ radiator ceiling + bed warmer + Hotline&#174;) has many drawbacks e.g.; slow and the working environment is hampered.The aim of this study was to compare our ordinary heating technique with newly-developed methods: the Allon&#8482;2001 Thermowrap (a temperature regulating water-mattress), and Warmcloud (a temperature regulating air-mattress).
Methods:
Ten consecutive burned patients (&gt; 20% total burned surface area and a core temperature &lt; 36.0&#176;C) were included in this prospective, randomised, comparative study. Patients were randomly exposed to 3 heating methods. Each treatment/measuring-cycle lasted for 6 hours. Each heating method was assessed for 2 hours according to a randomised timetable. Core temperature was measured using an indwelling (bladder) thermistor. Paired t-tests were used to assess the significance of differences between the treatments within the patients. ANOVA was used to assess the differences in temperature from the first to the last measurement among all treatments. Three-way ANOVA with the Tukey HSD post hoc test and a repeated measures ANOVA was used in the same manner, but included information about patients and treatment/measuring-cycles to control for potential confounding. Data are presented as mean (SD) and (range). Probabilities of less than 0.05 were accepted as significant.
Results:
The mean increase, 1.4 (SD 0.6&#176;C; range 0.6-2.6&#176;C) in core temperature/treatment/measuring-cycle highly significantly favoured the Allon&#8482;2001 Thermowrap in contrast to the conventional method 0.2 (0.6)&#176;C (range -1.2 to 1.5&#176;C) and the Warmcloud 0.3 (0.4)&#176;C (range -0.4 to 0.9&#176;C). The procedures for using the Allon&#8482;2001 Thermowrap were experienced to be more comfortable and straightforward than the conventional method or the Warmcloud.
Conclusions:
The Allon&#8482;2001 Thermowrap was more effective than the Warmcloud or the conventional method in controlling patients&apos; temperatures.</description>
        <link>http://www.asir-journal.com/content/5/1/4</link>
                <dc:creator>Britt-Marie Kjellman</dc:creator>
                <dc:creator>Mats Fredrikson</dc:creator>
                <dc:creator>Gunilla Glad Mattsson</dc:creator>
                <dc:creator>Folke Sjoberg</dc:creator>
                <dc:creator>Fredrik Huss</dc:creator>
                <dc:source>Annals of Surgical Innovation and Research 2011, null:4</dc:source>
        <dc:date>2011-07-07T00:00:00Z</dc:date>
        <dc:identifier>doi:10.1186/1750-1164-5-4</dc:identifier>
                            <dc:title>Managing hypothermia in burns patients</dc:title>
                            <dc:description>A newly developed temperature regulating water-mattress can be more effective than conventional heating methods in preventing hypothermia in patients with significant burns, by maintaining normal core body temperature.</dc:description>
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        <prism:startingPage>4</prism:startingPage>
        <prism:publicationDate>2011-07-07T00:00:00Z</prism:publicationDate>
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        <item rdf:about="http://www.asir-journal.com/content/3/1/7">
        <title>A versatile breast reduction technique: Conical plicated central U shaped (COPCUs) mammaplasty</title>
        <description>Background:
There have been numerous studies on reduction mammaplasty and its modifications in the literature. The multitude of modifications of reduction mammaplasty indicates that the ideal technique has yet to be found. There are four reasons for seeking the ideal technique. One reason is to preserve functional features of the breast: breastfeeding and arousal. Other reasons are to achieve the real geometric and aesthetic shape of the breast with the least scar and are to minimize complications of prior surgical techniques without causing an additional complication. Last reason is the limitation of the techniques described before. To these aims, we developed a new versatile reduction mammaplasty technique, which we called conical plicated central U shaped (COPCUs) mammaplasty.
Methods:
We performed central plication to achieve a juvenile look in the superior pole of the breast and to prevent postoperative pseudoptosis and used central U shaped flap to achieve maximum NAC safety and to preserve lactation and nipple sensation. The central U flap was 6 cm in width and the superior conical plication was performed with 2/0 PDS. Preoperative and postoperative standard measures of the breast including the superior pole fullness were compared.
Results:
Forty six patients were operated with the above mentioned technique. All of the patients were satisfied with functional and aesthetic results and none of them had major complications. There were no changes in the nipple innervation. Six patients becoming pregnant after surgery did not experience any problems with lactation. None of the patients required scar revision.
Conclusion:
Our technique is a versatile, safe, reliable technique which creates the least scar, avoids previously described disadvantages, provides maximum preservation of functions, can be employed in all breasts regardless of their sizes.</description>
        <link>http://www.asir-journal.com/content/3/1/7</link>
                <dc:creator>Eray Copcu</dc:creator>
                <dc:source>Annals of Surgical Innovation and Research 2009, null:7</dc:source>
        <dc:date>2009-07-03T00:00:00Z</dc:date>
        <dc:identifier>doi:10.1186/1750-1164-3-7</dc:identifier>
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        <prism:startingPage>7</prism:startingPage>
        <prism:publicationDate>2009-07-03T00:00:00Z</prism:publicationDate>
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                <cc:license rdf:resource="http://creativecommons.org/licenses/by/2.0/" />
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        <item rdf:about="http://www.asir-journal.com/content/3/1/15">
        <title>Emergency treatment of complicated incisional hernias: a case study</title>
        <description>Background:
The emergency treatment of incisional hernias is infrequent but it can be complicated with strangulation or obstruction and in some cases the surgical approach may also include an intestinal resection with the possibility of peritoneal contamination. Our study aims at reporting our experience in the emergency treatment of complicated incisional hernias.
Methods:
Since January 1999 till July 2008, 89 patients (55 males and 34 females) were treated for complicated incisional hernias in emergency. The patients were divided in two groups: Group I consisting of 33 patients that were treated with prosthesis apposition and Group II, consisting of 56 patients that were treated by performing a direct abdominal wall muscles suture.
Results:
All the patients underwent a 6-month follow up; we noticed 9 recurrences (9/56, 16%) in the patients treated with direct abdominal wall muscles suture and 1 recurrence (1/33, 3%) in the group of patients treated with the prosthesis apposition.
Conclusions:
According to our experience, the emergency treatment of complicated incisional hernias through prosthesis apposition is always feasible and ensures less post-operative complications (16% vs 21,2%) and recurrences (3% vs 16%) compared to the patients treated with direct muscular suture.</description>
        <link>http://www.asir-journal.com/content/3/1/15</link>
                <dc:creator>Francesco La Mura</dc:creator>
                <dc:creator>Roberto Cirocchi</dc:creator>
                <dc:creator>Eriberto Farinella</dc:creator>
                <dc:creator>Umberto Morelli</dc:creator>
                <dc:creator>Vincenzo Napolitano</dc:creator>
                <dc:creator>Lorenzo Cattorini</dc:creator>
                <dc:creator>Alessandro Spizzirri</dc:creator>
                <dc:creator>Barbara Rossetti</dc:creator>
                <dc:creator>Pamela Delmonaco</dc:creator>
                <dc:creator>Carla Migliaccio</dc:creator>
                <dc:creator>Diego Milani</dc:creator>
                <dc:creator>Piero Covarelli</dc:creator>
                <dc:creator>Carlo Boselli</dc:creator>
                <dc:creator>Giuseppe Noya</dc:creator>
                <dc:creator>Francesco Sciannameo</dc:creator>
                <dc:source>Annals of Surgical Innovation and Research 2009, null:15</dc:source>
        <dc:date>2009-12-17T00:00:00Z</dc:date>
        <dc:identifier>doi:10.1186/1750-1164-3-15</dc:identifier>
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        <prism:startingPage>15</prism:startingPage>
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        <item rdf:about="http://www.asir-journal.com/content/3/1/8">
        <title>Contamination of equipment in emergency settings: An exploratory study with a targeted automated intervention</title>
        <description>Background:
Despite standard manual decontamination, hospital equipment remains contaminated with microorganisms, contributing to nosocomial transmission and hospital acquired infections. This has the potential to negate the effects of healthcare workers&apos; hand-washing protocols. In order to decrease the likihood of equipment contamination, there has been a rise in the use of disposable pieces of equipment, especially non-critical disposables. However, these carry a significant cost, both a direct financial cost (running into billions of dollars), as well as a cost to the environment. This is important because we hope to contain the cost of healthcare, one way to do that, is to look to the hospitals themselves, for innovative solutions that maintain the standard of care.ObjectiveTo develop and evaluate the effectiveness of an simple decontamination device for use with portable hospital equipment, by comparing rates of residual contamination after use of the novel device versus those seen with standard manual decontamination methods.
Methods:
The Self-cleaning Unit for the Decontamination of Small instruments (SUDS) is a user-friendly, automated instrument developed via multi-disciplinary collaboration for decontamination in the clinical area. Pre- and post- utilization of portable medical equipment in an emergency department (ED) setting were cultured. To evaluate durability of the decrease in antimicrobial contamination, objects were re-cultured 48 hours after SUDS cleaning and following re-introduction into the clinical setting.
Results:
After manual decontamination, 25% (23/91) of the tested objects in the ED were found to be culture positive with clinically significant microorganisms(CSO). Fifteen percent (ED) of non-critical equipment tested had multiple organisms. Following the use of SUDS, the colonization rate decreased to 0%. Following SUDS treatment and re-introduction into the clinical settings, after 48 hours the contamination rates as reflected by the cultures remained 0%.
Conclusion:
Standard non-critical equipment is contaminated with clinically significant microorganisms. The SUDS device allows for effective and durable decontamination of hospital equipment of varying sizes in the clinical area without disrupting patient care.</description>
        <link>http://www.asir-journal.com/content/3/1/8</link>
                <dc:creator>Chidi Obasi</dc:creator>
                <dc:creator>Allison Agwu</dc:creator>
                <dc:creator>Wale Akinpelu</dc:creator>
                <dc:creator>Roger Hammons</dc:creator>
                <dc:creator>Clyde Clark</dc:creator>
                <dc:creator>Ralph Etienne-cummings</dc:creator>
                <dc:creator>Peter Hill</dc:creator>
                <dc:creator>Richard Rothman</dc:creator>
                <dc:creator>Stella Babalola</dc:creator>
                <dc:creator>Tracy Ross</dc:creator>
                <dc:creator>Karen Carroll</dc:creator>
                <dc:creator>Bolanle Asiyanbola</dc:creator>
                <dc:source>Annals of Surgical Innovation and Research 2009, null:8</dc:source>
        <dc:date>2009-07-30T00:00:00Z</dc:date>
        <dc:identifier>doi:10.1186/1750-1164-3-8</dc:identifier>
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        <prism:publicationDate>2009-07-30T00:00:00Z</prism:publicationDate>
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        <title>Antibiotic prophylaxis in thyroid surgery: a preliminary multicentric italian experience

</title>
        <description>Post-operatory wound infections are a very uncommon finding after thyroidectomy. For these reasons international guidelines do not routinely recommend systemic antibiotic prophylaxis.The benefits of this antibiotic prophylaxis is not supported by clinical evidence in the literature. We have conducted a multicentric randomized double-blind trial on 500 patients who had undergone thyroidectomy for goitre or thyroid carcinoma. The 500 patients enrolled in the study (mean age 47 years) were randomized in two subgroups of 250 patients. 250 patients were treated with standard antibiotic prophylaxis with sulbactam/ampicillin 1 fl (3 gr.) 30 min before surgery. No antibiotic prophylaxis was instituted in the remainder 250 patients. Our RCT showed that prophylactic antibiotic treatment is not beneficial in patients younger than eighty years old, with no concomitant metabolic, infective and hematologic disease, with no cardiac valvulopathies, not under steroidal or immunosuppressive treatment, and not severely obese. Our study should be regarded only as a preliminary RCT, and should be followed by a study in which a larger number of patients should be enrolled so that statistically significant data can be obtained.</description>
        <link>http://www.asir-journal.com/content/3/1/10</link>
                <dc:creator>Nicola Avenia</dc:creator>
                <dc:creator>Alessandro Sanguinetti</dc:creator>
                <dc:creator>Roberto Cirocchi</dc:creator>
                <dc:creator>Giovanni Docimo</dc:creator>
                <dc:creator>Mark Ragusa</dc:creator>
                <dc:creator>Roberto Ruggiero</dc:creator>
                <dc:creator>Eugenio Procaccini</dc:creator>
                <dc:creator>Carlo Boselli</dc:creator>
                <dc:creator>Fabio D'Ajello</dc:creator>
                <dc:creator>Francesco Barberini</dc:creator>
                <dc:creator>Domenico Parmeggiani</dc:creator>
                <dc:creator>Lodovico Rosato</dc:creator>
                <dc:creator>Francesco Sciannameo</dc:creator>
                <dc:creator>Giorgio De Toma</dc:creator>
                <dc:creator>Giuseppe Noya</dc:creator>
                <dc:source>Annals of Surgical Innovation and Research 2009, null:10</dc:source>
        <dc:date>2009-08-05T00:00:00Z</dc:date>
        <dc:identifier>doi:10.1186/1750-1164-3-10</dc:identifier>
                                <prism:require>/content/figures/1750-1164-3-10-toc.gif</prism:require>
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        <prism:startingPage>10</prism:startingPage>
        <prism:publicationDate>2009-08-05T00:00:00Z</prism:publicationDate>
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