Figure 3.

A. Logarithm concentration-response curves of substance P in strips from obese and control patients. Results shown are the mean of 6–8 strips from differenct patients, and the response is expressed as a percentage of the maximum response to carbachol (0.1 mmol/L). The differnces demonstrated are statistically significant. B – Cumulative concentrations of substance P have similar potency in obese and control tissues under NANC conditions. Results shown are a mean of 6–8 patients in each group, expressed as a percentage of the maximum response to carbachol (0.1 mmol/L). There are no statistically significant differences demonstrated under NANC conditions.