Topical recombinant thrombin at a concentration of 1000 IU/mL reliably shortens in vivo TTH and delivers durable hemostasis in the presence of heparin anticoagulation and clopidogrel platelet inhibition in a rabbit model of vascular bleeding

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Steven D Hughes, Paul D Bishop, Richard Garcia, Tracy Zhang and W Allan Alexander^*

Annals of Surgical Innovation and Research 2009, 3:14 doi:10.1186/1750-1164-3-14

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